TTI1 antibody (AA 692-858) (Biotin)

Catalog No. ABIN7171702

Product Details anti-TTI1 Antibody (Biotin)

Target: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Binding Specificity: AA 692-858

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TTI1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human TELO2-interacting protein 1 homolog protein (692-858AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TTI1

Target: TTI1 (TELO2 Interacting Protein 1 (TTI1))

Alternative Name: TTI1 (TTI1 Products)

Synonyms: KIAA0406 antibody, smg-10 antibody, 2610036D13Rik antibody, AI449463 antibody, RGD1562582 antibody, TELO2 interacting protein 1 antibody, TTI1 antibody, Tti1 antibody

Background:

Background: Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.

Aliases: TTI1 antibody, KIAA0406 antibody, SMG10 antibody, TELO2-interacting protein 1 homolog antibody, Protein SMG10 antibody

UniProt: O43156