TBC1D7 antibody (AA 1-293) (FITC)
-
- Target See all TBC1D7 Antibodies
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
-
Binding Specificity
- AA 1-293
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This TBC1D7 antibody is conjugated to FITC
- Application
- Please inquire
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human TBC1 domain family member 7 protein (1-293AA)
- Isotype
- IgG
- Top Product
- Discover our top product TBC1D7 Primary Antibody
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))
- Alternative Name
- TBC1D7 (TBC1D7 Products)
- Synonyms
- PIG51 antibody, TBC7 antibody, dJ257A7.3 antibody, 2610009C09Rik antibody, TBC1 domain family member 7 antibody, TBC1 domain family, member 7 antibody, TBC1D7 antibody, Tbc1d7 antibody
- Background
-
Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.
Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody
- UniProt
- Q9P0N9
-