ESRRA antibody (AA 1-423)

Catalog No. ABIN7170761

Product Details anti-ESRRA Antibody

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Binding Specificity: AA 1-423

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESRRA antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Steroid hormone receptor ERR1 protein (1-423AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Alternative Name: ESRRA (ESRRA Products)

Synonyms: err1 antibody, erra antibody, esrral antibody, erralpha antibody, nr3b1 antibody, MGC80854 antibody, ESRRA antibody, esrl1 antibody, LOC100125507 antibody, ERRalpha antibody, Err1 antibody, Estrra antibody, Nr3b1 antibody, Errra antibody, ERR1 antibody, ERRa antibody, ESRL1 antibody, NR3B1 antibody, ESTRRA antibody, estrogen-related receptor alpha antibody, estrogen related receptor alpha L homeolog antibody, estrogen related receptor alpha antibody, catsper channel auxiliary subunit zeta antibody, estrogen related receptor, alpha antibody, esrra antibody, esrra.L antibody, ESRRA antibody, LOC100125507 antibody, CATSPERZ antibody, Esrra antibody

Background:

Background: Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5\\\'-TNAAGGTCA-3\\\'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. Binds to the C1 region of the lactoferrin gene promoter. Requires dimerization and the coactivator, PGC-1A, for full activity. The ERRalpha/PGC1alpha complex is a regulator of energy metabolism. Induces the expression of PERM1 in the skeletal muscle.

Aliases: Err 1 antibody, ERR a antibody, ERR alpha antibody, ERR-alpha antibody, Err1 antibody, ERR1 protein antibody, ERR1_HUMAN antibody, ERRa antibody, ERRalpha antibody, ESRL 1 antibody, ESRL1 antibody, ESRR A antibody, Esrra antibody, Estrogen receptor like 1 antibody, Estrogen receptor related 1 antibody, estrogen receptor related receptor alpha antibody, Estrogen receptor-like 1 antibody, Estrogen related receptor alpha antibody, Estrogen-related receptor alpha antibody, Estrra antibody, hERR1 antibody, NR3B1 antibody, Nuclear receptor subfamily 3 group B member 1 antibody, Steroid hormone receptor ERR1 antibody

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha