SMPD3 antibody (AA 401-655)

Catalog No. ABIN7170557

Product Details anti-SMPD3 Antibody

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Binding Specificity: AA 401-655

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sphingomyelin phosphodiesterase 3 protein (401-655AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:50-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMPD3

Target: SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))

Alternative Name: SMPD3 (SMPD3 Products)

Synonyms: 4631433G07Rik antibody, AI427456 antibody, AW537966 antibody, fro antibody, nSMase2 antibody, cca1 antibody, NSMASE2 antibody, sphingomyelin phosphodiesterase 3 antibody, sphingomyelin phosphodiesterase 3, neutral antibody, SMPD3 antibody, Smpd3 antibody

Background:

Background: Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.

Aliases: Cca1 antibody, Confluent 3Y1 cell-associated protein 1 antibody, Neutral sphingomyelinase 2 antibody, Neutral sphingomyelinase II antibody, NSMA2_HUMAN antibody, nSMase-2 antibody, nSMase2 antibody, SMPD3 antibody, Sphingomyelin phosphodiesterase 3 antibody, sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) antibody

UniProt: Q9NY59

Pathways: Hormone Transport