SMPD2 antibody (AA 199-301)

Catalog No. ABIN7170553

Product Details anti-SMPD2 Antibody

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Binding Specificity: AA 199-301

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMPD2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sphingomyelin phosphodiesterase 2 protein (199-301AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SMPD2

Target: SMPD2 (Sphingomyelin phosphodiesterase 2, Neutral Membrane (Neutral Sphingomyelinase) (SMPD2))

Alternative Name: SMPD2 (SMPD2 Products)

Synonyms: SMPD2 antibody, NSMase antibody, isc1 antibody, nsmase antibody, nsmase1 antibody, AW108287 antibody, nSMase antibody, nSMase1 antibody, ISC1 antibody, NSMASE antibody, NSMASE1 antibody, sphingomyelin phosphodiesterase 2 antibody, sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase) antibody, sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) antibody, sphingomyelin phosphodiesterase 2, neutral antibody, SMPD2 antibody, smpd2a antibody, smpd2 antibody, Smpd2 antibody

Background:

Background: Converts sphingomyelin to ceramide. Hydrolyze 1-acyl-2-lyso-sn-glycero-3-phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine (lyso-platelet-activating factor). The physiological substrate seems to be Lyso-PAF.

Aliases: ISC1 antibody, Lyso platelet activating factor phospholipase C antibody, Lyso-PAF-PLC antibody, Lyso-platelet-activating factor-phospholipase C antibody, N-SMase antibody, Neutral sphingomyelinase antibody, NSMA_HUMAN antibody, nSMase antibody, NSMASE1 antibody, Smpd2 antibody, Sphingomyelin phosphodiesterase 2 antibody, Sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) antibody

UniProt: O60906

Pathways: Neurotrophin Signaling Pathway