SNX14 antibody (AA 601-893) (Biotin)

Catalog No. ABIN7170353

Product Details anti-SNX14 Antibody (Biotin)

Target: SNX14 (Sorting Nexin 14 (SNX14))

Binding Specificity: AA 601-893

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNX14 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sorting nexin-14 protein (601-893AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SNX14

Target: SNX14 (Sorting Nexin 14 (SNX14))

Alternative Name: SNX14 (SNX14 Products)

Synonyms: SNX14 antibody, si:ch211-241p10.3 antibody, snx14 antibody, MGC146224 antibody, RGS-PX2 antibody, B830022K16 antibody, C330035N22Rik antibody, YR-14 antibody, sorting nexin 14 antibody, sorting nexin 14 L homeolog antibody, Snx14 antibody, SNX14 antibody, snx14.L antibody, snx14 antibody

Background:

Background: Plays a role in maintaining normal neuronal excitability and synaptic transmission. May be involved in several stages of intracellular trafficking (By similarity). Required for autophagosome clearance, possibly by mediating the fusion of lysosomes with autophagosomes (Probable). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2), a key component of late endosomes/lysosomes (PubMed:25848753). Does not bind phosphatidylinositol 3-phosphate (PtdIns(3P)) (PubMed:25848753, PubMed:25148684).

Aliases: MGC13217 antibody, RGS-PX2 antibody, RP11-321N4.2 antibody, Snx14 antibody, SNX14_HUMAN antibody, Sorting nexin 14 antibody, Sorting nexin-14 antibody

UniProt: Q9Y5W7

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling