SUMO3 antibody (AA 1-92)

Catalog No. ABIN7169889

Product Details anti-SUMO3 Antibody

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Binding Specificity: AA 1-92

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUMO3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Small ubiquitin-related modifier 3 protein (1-92AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUMO3

Target: SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))

Alternative Name: SUMO3 (SUMO3 Products)

Background:

Background: Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Does not seem to be involved in protein degradation and may function as an antagonist of ubiquitin in the degradation process. Plays a role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Covalent attachment to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4 (PubMed:11451954, PubMed:18538659, PubMed:21965678). Plays a role in the regulation of sumoylation status of SETX (PubMed:24105744).

Aliases: Small ubiquitin like modifier 3 antibody, Small ubiquitin related modifier 3 antibody, Small ubiquitin-related modifier 3 antibody, SMT3 homolog 1 antibody, SMT3 suppressor of mif two 3 homolog 1 antibody, SMT3 suppressor of mif two 3 homolog 3 antibody, SMT3, yeast, homolog 1 antibody, SMT3A antibody, Smt3B antibody, SMT3H1 antibody, SUMO-2 antibody, SUMO-3 antibody, sumo3 antibody, SUMO3_HUMAN antibody, Ubiquitin like protein SMT3A antibody, Ubiquitin-like protein SMT3B antibody

UniProt: P55854