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SMUG1 antibody (AA 1-177) (Biotin)

SMUG1 Reactivity: Human ELISA Host: Rabbit Polyclonal Biotin
Catalog No. ABIN7169741
  • Target See all SMUG1 Antibodies
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Binding Specificity
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-177
    Reactivity
    • 46
    • 18
    • 17
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 40
    • 5
    • 1
    Rabbit
    Clonality
    • 44
    • 2
    Polyclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMUG1 antibody is conjugated to Biotin
    Application
    • 33
    • 23
    • 5
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Single-strand selective monofunctional uracil DNA glycosylase protein (1-177AA)
    Isotype
    IgG
    Top Product
    Discover our top product SMUG1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1 (SMUG1))
    Alternative Name
    SMUG1 (SMUG1 Products)
    Synonyms
    SMUG1 antibody, xsmug1 antibody, 1200013B09Rik antibody, A930006H09Rik antibody, C85220 antibody, FDG antibody, HMUDG antibody, UNG3 antibody, single-strand-selective monofunctional uracil-DNA glycosylase 1 antibody, single-strand selective monofunctional uracil DNA glycosylase antibody, single-strand-selective monofunctional uracil-DNA glycosylase 1 L homeolog antibody, SMUG1 antibody, smug1 antibody, smuG1 antibody, smuG antibody, LOC5577584 antibody, CpipJ_CPIJ002767 antibody, Smug1 antibody, smug1.L antibody
    Background

    Background: Recognizes base lesions in the genome and initiates base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA with a preference for single-stranded DNA substrates. The activity is greater toward mismatches (U/G) compared to matches (U/A). Excises uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5-hydroxymethyluracil (hmU)] in ssDNA and dsDNA, but not analogous cytosine derivatives (5-hydroxycytosine and 5-formylcytosine), nor other oxidized bases. The activity is damage-specific and salt-dependent. The substrate preference is the following: ssDNA > dsDNA (G pair) = dsDNA (A pair) at low salt concentration, and dsDNA (G pair) > dsDNA (A pair) > ssDNA at high salt concentration.

    Aliases: FDG antibody, HMUDG antibody, MGC104370 antibody, Single strand selective monofunctional uracil DNA glycosylase 1 antibody, Single strand selective monofunctional uracil DNA glycosylase antibody, Single-strand selective monofunctional uracil DNA glycosylase antibody, SMUG 1 antibody, Smug1 antibody, SMUG1 protein antibody, SMUG1_HUMAN antibody, UNG 3 antibody, UNG3 antibody

    UniProt
    Q53HV7
    Pathways
    DNA Damage Repair
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