Sialoadhesin/CD169 antibody (AA 572-697)

Catalog No. ABIN7169553

Product Details anti-Sialoadhesin/CD169 Antibody

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Binding Specificity: AA 572-697

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sialoadhesin/CD169 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Sialic acid-binding Ig-like lectin 10 protein (572-697AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Sialoadhesin/CD169

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Alternative Name: SIGLEC1 (SIGLEC1 Products)

Synonyms: Cd169 antibody, Siglec-1 antibody, Sn antibody, CD169 antibody, SIGLEC-1 antibody, SN antibody, dJ1009E24.1 antibody, SA antibody, SIGLEC1 antibody, p210 antibody, pSn antibody, sialic acid binding Ig like lectin 1 antibody, sialic acid binding Ig-like lectin 1, sialoadhesin antibody, SIGLEC1 antibody, Siglec1 antibody

Background:

Background: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Aliases: mSiglec G antibody, PRO940 antibody, Sialic acid binding Ig like lectin 10 antibody, Sialic acid binding Ig like lectin 10 antibody, sialic acid binding Ig like lectin 10 Ig like lectin 7 antibody, sialic acid binding Ig like lectin G antibody, Sialic acid binding Immunoglobulin like lectin 10 antibody, Sialic acid-binding Ig-like lectin 10 antibody, SIG10_HUMAN antibody, SIGLEC 10 antibody, Siglec G antibody, siglec like gene 2 antibody, Siglec like protein 2 antibody, Siglec like protein 2 antibody, Siglec-10 antibody, Siglec-like protein 2 antibody, SIGLEC10 antibody, Siglecg antibody, SLG2 antibody

UniProt: Q96LC7