SESN3 antibody (AA 1-310)

Catalog No. ABIN7169409

Product Details anti-SESN3 Antibody

Target: SESN3 (Sestrin 3 (SESN3))

Binding Specificity: AA 1-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SESN3 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Sestrin-3 protein (1-310AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SESN3

Target: SESN3 (Sestrin 3 (SESN3))

Alternative Name: SESN3 (SESN3 Products)

Synonyms: cb261 antibody, sb:cb261 antibody, zgc:56722 antibody, wu:fb77c04 antibody, wu:fc41d03 antibody, wu:fd59d12 antibody, sestrin-3 antibody, sest3 antibody, SEST3 antibody, 5630400E15Rik antibody, BC003348 antibody, sestrin 3 antibody, sestrin 3 L homeolog antibody, SESN3 antibody, sesn3 antibody, sesn3.L antibody, Sesn3 antibody

Background:

Background: Sestrins, including sestrin-1 (PA26), sestrin-2 (Hi95), and sestrin-3, are 48 to 65 kDa cystein sulfinyl reductases and they modulate peroxide signaling and antioxidant defense. These proteins selectively reduce or repair hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. Expression of these proteins is regulated by p53, a tumor suppressor protein. Sestrin 3 was identified as a forkhead box O (FoxO) target gene with antioxidant activity.

Aliases: MGC29667 antibody, OTTHUMP00000236979 antibody, OTTHUMP00000236986 antibody, SESN3 antibody, SESN3_HUMAN antibody, SEST3 antibody, Sestrin 3 antibody, Sestrin-3 antibody

UniProt: P58005