PGAM5 antibody (AA 30-223)

Catalog No. ABIN7169300

Product Details anti-PGAM5 Antibody

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Binding Specificity: AA 30-223

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PGAM5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein phosphatase PGAM5, mitochondrial protein (30-223AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PGAM5

Target: PGAM5 (Phosphoglycerate Mutase Family Member 5 (PGAM5))

Alternative Name: PGAM5 (PGAM5 Products)

Synonyms: CG14816 antibody, DPGAM5 antibody, Dmel\\CG14816 antibody, EG:63B12.4 antibody, PGAM5 antibody, dPGAM5 antibody, BXLBV68 antibody, 2610528A17Rik antibody, RGD1312028 antibody, si:dkey-69p22.1 antibody, wu:fb39f09 antibody, wu:fj34f06 antibody, zgc:112041 antibody, zgc:92057 antibody, Phosphoglycerate mutase 5 antibody, PGAM family member 5, mitochondrial serine/threonine protein phosphatase antibody, phosphoglycerate mutase family member 5 antibody, PGAM family member 5, serine/threonine protein phosphatase, mitochondrial S homeolog antibody, PGAM family member 5, serine/threonine protein phosphatase, mitochondrial antibody, Pgam5 antibody, PGAM5 antibody, pgam5.S antibody, pgam5 antibody

Background:

Background: Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.

Aliases: Bcl-XL-binding protein v68 antibody, BXLBv68 antibody, MGC5352 antibody, mitochondrial antibody, PGAM5 antibody, PGAM5_HUMAN antibody, Phosphoglycerate mutase family member 5 antibody, Serine/threonine protein phosphatase PGAM5 mitochondrial antibody, Serine/threonine-protein phosphatase PGAM5 antibody

UniProt: Q96HS1