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ULK3 antibody (AA 44-240)

ULK3 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7169213
  • Target See all ULK3 Antibodies
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Binding Specificity
    • 14
    • 11
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-240
    Reactivity
    • 54
    • 46
    • 16
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 61
    • 7
    • 2
    Rabbit
    Clonality
    • 64
    • 6
    Polyclonal
    Conjugate
    • 31
    • 6
    • 6
    • 6
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ULK3 antibody is un-conjugated
    Application
    • 62
    • 39
    • 10
    • 10
    • 9
    • 6
    • 3
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Antigen Affinity Purified
    Immunogen
    Recombinant Human Serine/threonine-protein kinase ULK3 protein (44-240AA)
    Isotype
    IgG
    Top Product
    Discover our top product ULK3 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    ULK3 (Unc-51-Like Kinase 3 (ULK3))
    Alternative Name
    ULK3 (ULK3 Products)
    Synonyms
    zgc:162196 antibody, 1200015E14Rik antibody, unc-51 like kinase 3 antibody, unc-51 like kinase 3 L homeolog antibody, unc-51-like kinase 3 antibody, ULK3 antibody, ulk3 antibody, Ulk3 antibody, ulk3.L antibody
    Background

    Background: Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.

    Aliases: DKFZP434C131 antibody, FLJ90566 antibody, Serine/threonine-protein kinase ULK3 antibody, Ulk3 antibody, ULK3_HUMAN antibody, unc 51 like kinase 3 (C. elegans) antibody, Unc-51-like kinase 3 antibody

    UniProt
    Q6PHR2
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