PAK6 antibody (AA 1-270)

Catalog No. ABIN7169136

Product Details anti-PAK6 Antibody

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Binding Specificity: AA 1-270

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Serine/threonine-protein kinase PAK 6 protein (1-270AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Alternative Name: PAK6 (PAK6 Products)

Synonyms: PAK5 antibody, 4732456M09 antibody, pak6 antibody, si:ch211-158b22.3 antibody, p21 (RAC1) activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6b antibody, PAK6 antibody, Pak6 antibody, pak6b antibody

Background:

Background: Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Aliases: CDKN1A activated kinase 6 antibody, EC 2.7.1.37 antibody, p21 activated protein kinase 6 antibody, p21 protein (Cdc42/Rac)-activated kinase 6 antibody, p21(CDKN1A) activated kinase 6 antibody, p21-activated kinase 6 antibody, p21activated kinase 6 antibody, PAK 5 antibody, PAK 6 antibody, PAK-5 antibody, PAK-6 antibody, PAK5 antibody, Pak6 antibody, PAK6_HUMAN antibody, Serine threonine protein kinase PAK 6 antibody, Serine/threonine protein kinase PAK 6 antibody, Serine/threonine protein kinase PAK6 antibody, Serine/threonine-protein kinase PAK 6 antibody

UniProt: Q9NQU5