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MASTL antibody (AA 612-740) (HRP)

MASTL Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7169046
  • Target See all MASTL Antibodies
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 612-740
    Reactivity
    • 45
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 14
    Rabbit
    Clonality
    • 44
    • 15
    Polyclonal
    Conjugate
    • 26
    • 7
    • 6
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MASTL antibody is conjugated to HRP
    Application
    • 46
    • 37
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Serine/threonine-protein kinase greatwall protein (612-740AA)
    Isotype
    IgG
    Top Product
    Discover our top product MASTL Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MASTL (Microtubule Associated serine/threonine Kinase-Like (MASTL))
    Alternative Name
    MASTL (MASTL Products)
    Synonyms
    GW antibody, GWL antibody, MAST-L antibody, im:7149025 antibody, wu:fa02a12 antibody, zgc:100990 antibody, MASTL antibody, GREATWALL antibody, RP11-85G18.2 antibody, THC2 antibody, hGWL antibody, 2700091H24Rik antibody, C88295 antibody, greatwall antibody, thc2 antibody, microtubule associated serine/threonine kinase-like antibody, microtubule associated serine/threonine kinase like antibody, serine/threonine-protein kinase greatwall antibody, microtubule associated serine/threonine kinase like L homeolog antibody, mastl antibody, MASTL antibody, LOC100541707 antibody, Mastl antibody, mastl.L antibody
    Background

    Background: Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at \'Ser-62\' and \'Ser-67\', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro, however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.

    Aliases: 2700091H24Rik antibody, C88295 antibody, FLJ14813 antibody, GREATWALL antibody, Greatwall protein kinase antibody, GW antibody, GWL antibody, GWL_HUMAN antibody, hGWL antibody, MAST-L antibody, Mastl antibody, MGC117975 antibody, Microtubule associated serine/threonine kinase like antibody, Microtubule-associated serine/threonine-protein kinase-like antibody, RP11 85G18.2 antibody, Serine/threonine-protein kinase greatwall antibody, THC2 antibody

    UniProt
    Q96GX5
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