Hepsin antibody (AA 294-413) (Biotin)

Catalog No. ABIN7168913

Product Details anti-Hepsin Antibody (Biotin)

Target: Hepsin (HPN)

Binding Specificity: AA 294-413

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Hepsin antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Serine protease hepsin protein (294-413AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Hepsin

Target: Hepsin (HPN)

Alternative Name: HPN (HPN Products)

Synonyms: TMPRSS1 antibody, Hlb320 antibody, hepsin antibody, si:dkey-33i11.3 antibody, HPN antibody, si:dkey-33i11.3 antibody, Hpn antibody

Background:

Background: Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL (PubMed:21875933, PubMed:15839837). Plays a role in cell growth and maintenance of cell morphology (PubMed:8346233, PubMed:21875933). Plays a role in the proteolytic processing of ACE2 (PubMed:24227843). Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization (PubMed:26673890).

Aliases: EC 3.4.21. antibody, HEPS antibody, HEPS_HUMAN antibody, Hepsin antibody, Hpn antibody, Serine protease hepsin antibody, Serine protease hepsin catalytic chain antibody, Serine protease hepsin non catalytic chain antibody, TMPRSS 1 antibody, TMPRSS1 antibody, Transmembrane protease serine 1 antibody

UniProt: P05981

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound