SRGN antibody (AA 28-158)

Catalog No. ABIN7168879

Product Details anti-SRGN Antibody

Target: SRGN (serglycin (SRGN))

Binding Specificity: AA 28-158

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Serglycin protein (28-158AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN (SRGN Products)

Synonyms: PPG antibody, PRG antibody, PRG1 antibody, Prg antibody, Prg1 antibody, Sgc antibody, Pgsg antibody, serglycin antibody, SRGN antibody, Srgn antibody

Background:

Background: Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.

Aliases: Chondroitin sulfate proteoglycan core protein antibody, Cytolytic granule proteoglycan core protein antibody, FLJ12930 antibody, gp600 antibody, Hematopoetic proteoglycan core protein antibody, Mastocytoma proteoglycan core protein antibody, MGC9289 antibody, OTTHUMP00000019716 antibody, P.PG antibody, PG19 core protein antibody, Pgsg antibody, Platelet proteoglycan core protein antibody, platelet proteoglycan protein core antibody, PLATELET PROTEOGLYCAN PROTEIN CORE, PPG antibody, PPG antibody, PRG antibody, PRG1 antibody, PROTEOGLYCAN 1 antibody, proteoglycan 1, secretory granule antibody, Proteoglycan 10K core protein antibody, Proteoglycan peptide core protein antibody, PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE antibody, secretory granule proteoglycan 1 antibody, Secretory granule proteoglycan core peptide antibody, Secretory granule proteoglycan core protein antibody, Serglycin antibody, serglycin proteoglycan antibody, Sgc antibody, Srgn antibody, SRGN_HUMAN antibody

UniProt: P10124

Pathways: Maintenance of Protein Location