RRM1 antibody
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- Target See all RRM1 Antibodies
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RRM1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Protein G purified
- Immunogen
- Recombinant Human RRM1 Protein
- Clone
- 3D6H5
- Isotype
- IgG
- Top Product
- Discover our top product RRM1 Primary Antibody
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- Application Notes
- Recommended dilution:IHC:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Alternative Name
- RRM1 (RRM1 Products)
- Synonyms
- CG5371 antibody, DmRNR1 antibody, Dmel\\CG5371 antibody, RNR1 antibody, RnrM1 antibody, RntL antibody, l(2)k06709 antibody, XRRM1 antibody, R1 antibody, RIR1 antibody, RR1 antibody, CHUNP6866 antibody, cb396 antibody, cb838 antibody, r1 antibody, sb:cb548 antibody, wu:fb39b07 antibody, wu:fi14b02 antibody, wu:fk95f07 antibody, ribonucleotide reductase catalytic subunit M1 antibody, Ribonucleoside diphosphate reductase large subunit antibody, ribonucleoside-diphosphate reductase large subunit antibody, ribonucleotide reductase M1 L homeolog antibody, ribonucleotide reductase M1 antibody, ribonucleotide reductase M1 polypeptide antibody, RRM1 antibody, RnrL antibody, LOC100472317 antibody, rrm1 antibody, rrm1.L antibody, Rrm1 antibody
- Background
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Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Aliases: Ribonucleotide Reductase M1,RRM1,RR1
- UniProt
- P23921
- Pathways
- Positive Regulation of Endopeptidase Activity
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