RRM1 antibody
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- Target See all RRM1 Antibodies
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This RRM1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Protein G purified
- Immunogen
- Recombinant Human RRM1 Protein
- Clone
- 3D6H5
- Isotype
- IgG
- Top Product
- Discover our top product RRM1 Primary Antibody
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- Application Notes
- Recommended dilution:IHC:1:50-1:500,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- RRM1 (Ribonucleotide Reductase M1 (RRM1))
- Alternative Name
- RRM1 (RRM1 Products)
- Background
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Background: This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.
Aliases: Ribonucleotide Reductase M1,RRM1,RR1
- UniProt
- P23921
- Pathways
- Positive Regulation of Endopeptidase Activity
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