RNF7 antibody (AA 2-113)

Catalog No. ABIN7168264

Product Details anti-RNF7 Antibody

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Binding Specificity: AA 2-113

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human RING-box protein 2 protein (2-113AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:500-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Alternative Name: RNF7 (RNF7 Products)

Synonyms: CKBBP1 antibody, ROC2 antibody, SAG antibody, Rbx2 antibody, ring finger protein 7 antibody, RNF7 antibody, Rnf7 antibody

Background:

Background: Probable component of the SCF E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Aliases: CKBBP 1 antibody, CKBBP1 antibody, CKII beta binding protein 1 antibody, CKII beta-binding protein 1 antibody, Rbx 2 antibody, Rbx2 antibody, RBX2_HUMAN antibody, Regulator of cullins 2 antibody, RING box protein 2 antibody, RING finger protein 7 antibody, RING-box protein 2 antibody, RNF 7 antibody, RNF7 antibody, ROC 2 antibody, ROC2 antibody, SAG antibody, Sensitive to apoptosis gene antibody, Sensitive to apoptosis gene protein antibody, Zinc RING finger protein SAG antibody

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity