SBDS antibody (AA 37-153)

Catalog No. ABIN7168210

Product Details anti-SBDS Antibody

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Binding Specificity: AA 37-153

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBDS antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ribosome maturation protein SBDS protein (37-153AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SBDS

Target: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Alternative Name: SBDS (SBDS Products)

Synonyms: cgi-97 antibody, sds antibody, swds antibody, zgc:56700 antibody, SDS antibody, SWDS antibody, 4733401P19Rik antibody, AI836084 antibody, CGI-97 antibody, SBDS ribosome assembly guanine nucleotide exchange factor antibody, hypothetical protein antibody, SBDS, ribosome maturation factor antibody, SBDS ribosome assembly guanine nucleotide exchange factor S homeolog antibody, SBDS ribosome maturation factor antibody, sbds antibody, LOAG_04440 antibody, sbds.S antibody, SBDS antibody, Sbds antibody

Background:

Background: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

Aliases: 4733401P19Rik antibody, AI836084 antibody, CGI 97 antibody, CGI-97 antibody, FLJ10917 antibody, MGC105922 antibody, Protein 22A3 antibody, Ribosome maturation protein SBDS antibody, sbds antibody, SBDS_HUMAN antibody, SDS antibody, Shwachman Bodian Diamond syndrome protein antibody, Shwachman Bodian Diamond syndrome protein homolog antibody, Shwachman Bodian-Diamond syndrome antibody, Shwachman-Bodian-Diamond syndrome protein antibody, SWDS antibody

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly