Ribonuclease H1 antibody (AA 73-185) (Biotin)

Catalog No. ABIN7168104

Product Details anti-Ribonuclease H1 Antibody (Biotin)

Target: Ribonuclease H1 (RNASEH1)

Binding Specificity: AA 73-185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ribonuclease H1 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ribonuclease H1 protein (73-185AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Ribonuclease H1

Target: Ribonuclease H1 (RNASEH1)

Alternative Name: RNASEH1 (RNASEH1 Products)

Synonyms: H1RNA antibody, RNH1 antibody, 74/9 antibody, CG8729 antibody, Dmel\\CG8729 antibody, RNase H1 antibody, RnH1 antibody, l(2)43F1-5 antibody, l(2)43Fa antibody, l(2)k07409 antibody, l(2)k07624 antibody, rnhl antibody, h1rna antibody, rnh1 antibody, zgc:91971 antibody, RNASEH1P1 antibody, RNASEH1 antibody, rnaseh1 antibody, Afu1g10020 antibody, Tb07.26A24.40 antibody, ribonuclease H1 antibody, ribonuclease H1 S homeolog antibody, ribonuclease H1 L homeolog antibody, ribonuclease HI antibody, Ribonuclease H1 antibody, RNASEH1 antibody, Rnaseh1 antibody, rnh1 antibody, rnaseh1.S antibody, rnaseh1 antibody, rnaseh1.L antibody, AFUA_1G10020 antibody, Tb927.7.4930 antibody, APH_RS00510 antibody

Background:

Background: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224).

Aliases: RNASEH1 antibody, RNH1 antibody, Ribonuclease H1 antibody, RNase H1 antibody, EC 3.1.26.4 antibody, Ribonuclease H type II antibody

UniProt: O60930