Riboflavin Kinase antibody (AA 1-154)

Catalog No. ABIN7168091

Product Details anti-Riboflavin Kinase Antibody

Target: Riboflavin Kinase (RFK)

Binding Specificity: AA 1-154

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Riboflavin Kinase antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Riboflavin kinase protein (1-154AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Riboflavin Kinase

Target: Riboflavin Kinase (RFK)

Alternative Name: RFK (RFK Products)

Synonyms: RFK antibody, 0610038L10Rik antibody, AF031381 antibody, KOI-4 antibody, RIFK antibody, riboflavin kinase antibody, FMN adenylyltransferase antibody, Riboflavin kinase antibody, RFK antibody, ribF antibody, CNC05850 antibody, Nitsa_1631 antibody, Isop_1070 antibody, Rfk antibody

Background:

Background: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.

Aliases: 0610038L10Rik antibody, AF031381 antibody, ATP:riboflavin 5' phosphotransferase antibody, ATP:riboflavin 5''-phosphotransferase antibody, Flavokinase antibody, FLJ11149 antibody, KOI 4 antibody, Rfk antibody, Riboflavin kinase antibody, RIFK antibody, RIFK_HUMAN antibody, RP11-422N19.2 antibody

UniProt: Q969G6