ARHGEF12 antibody (AA 1302-1501)

Catalog No. ABIN7167968

Product Details anti-ARHGEF12 Antibody

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Binding Specificity: AA 1302-1501

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 12 protein (1302-1501AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for ARHGEF12

Target: ARHGEF12 (rho Guanine Nucleotide Exchange Factor (GEF) 12 (ARHGEF12))

Alternative Name: ARHGEF12 (ARHGEF12 Products)

Synonyms: larg antibody, ARHGEF12 antibody, Larg antibody, pro2792 antibody, LARG antibody, PRO2792 antibody, 2310014B11Rik antibody, AU019857 antibody, mKIAA0382 antibody, Rho guanine nucleotide exchange factor 12 S homeolog antibody, Rho guanine nucleotide exchange factor 12 antibody, Rho guanine nucleotide exchange factor (GEF) 12 antibody, arhgef12.S antibody, ARHGEF12 antibody, arhgef12 antibody, Arhgef12 antibody

Background:

Background: May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.

Aliases: ARHGC_HUMAN antibody, ARHGEF12 antibody, KIAA0382 antibody, leukemia-associated rho guanine nucleotide exchange factor antibody, Leukemia-associated RhoGEF antibody, PRO2792 antibody, Rho guanine exchange factor (GEF) 12 antibody, Rho guanine nucleotide exchange factor (GEF) 12 antibody, Rho guanine nucleotide exchange factor 12 antibody, Similar to Mouse Lsc oncogene antibody

UniProt: Q9NZN5

Pathways: Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling