Retinoic Acid Receptor beta antibody (AA 1-85)

Catalog No. ABIN7167799

Product Details anti-Retinoic Acid Receptor beta Antibody

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Binding Specificity: AA 1-85

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoic Acid Receptor beta antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Retinoic acid receptor beta protein (1-85AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Retinoic Acid Receptor beta

Target: Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))

Alternative Name: RARB (RARB Products)

Synonyms: RARB antibody, nRARs antibody, HAP antibody, NR1B2 antibody, RRB2 antibody, A830025K23 antibody, Hap antibody, Nr1b2 antibody, RARbeta2 antibody, RARBETA antibody, retinoic acid receptor beta antibody, retinoic acid receptor, beta antibody, RARB antibody, Rarb antibody

Background:

Background: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5\'-AGGTCA-3\' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Aliases: HAP antibody, HBV-activated protein antibody, NR1B2 antibody, Nuclear receptor subfamily 1 group B member 2 antibody, RAR B antibody, RAR beta antibody, RAR epsilon antibody, RAR-beta antibody, RAR-epsilon antibody, RARB antibody, RARB_HUMAN antibody, Retinoic acid receptor beta 2 antibody, Retinoic acid receptor beta 4 antibody, Retinoic acid receptor beta 5 antibody, Retinoic acid receptor beta antibody, Retinoic acid receptor beta polypeptide antibody, RRB2 antibody

UniProt: P10826

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway