FAM134B antibody (AA 1-131)

Catalog No. ABIN7167757

Product Details anti-FAM134B Antibody

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Binding Specificity: AA 1-131

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM134B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Reticulophagy receptor FAM134B protein (1-131AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for FAM134B

Target: FAM134B (Family with Sequence Similarity 134, Member B (FAM134B))

Alternative Name: RETREG1 (FAM134B Products)

Synonyms: JK-1 antibody, JK1 antibody, 1810015C04Rik antibody, AU015349 antibody, reticulophagy regulator 1 antibody, family with sequence similarity 134, member B antibody, RETREG1 antibody, Retreg1 antibody, Fam134b antibody

Background:

Background: Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).

Aliases: F134B_HUMAN antibody, FAM134B antibody, family with sequence similarity 134 member B antibody, HSAN2B antibody, JK 1 antibody, JK1 antibody, Protein FAM134B antibody

UniProt: Q9H6L5