RNLS antibody (AA 18-342)

Catalog No. ABIN7167670

Product Details anti-RNLS Antibody

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Binding Specificity: AA 18-342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNLS antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Renalase protein (18-342AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Alternative Name: RNLS (RNLS Products)

Synonyms: zgc:92286 antibody, C10orf59 antibody, RENALASE antibody, 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, RGD1309804 antibody, renalase, FAD dependent amine oxidase antibody, renalase, FAD-dependent amine oxidase antibody, RNLS antibody, rnls antibody, Rnls antibody

Background:

Background: Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.

Aliases: 6530404N21Rik antibody, AI452315 antibody, AW060440 antibody, C10orf59 antibody, Chromosome 10 open reading frame 59 antibody, FLJ11218 antibody, HGNC:25641 antibody, Hypothetical protein LOC55328 antibody, MAO C antibody, MAO-C antibody, mMAO C antibody, Monoamine oxidase C antibody, Monoamine oxidase-C antibody, Renalase antibody, Renalase FAD dependent amine oxidase antibody, RNLS antibody, RNLS_HUMAN antibody

UniProt: Q5VYX0