RGS2 antibody (AA 1-211)

Catalog No. ABIN7167601

Product Details anti-RGS2 Antibody

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Binding Specificity: AA 1-211

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Regulator of G-protein signaling 2 protein (1-211AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS2

Target: RGS2 (Regulator of G-Protein Signaling 2 (RGS2))

Alternative Name: RGS2 (RGS2 Products)

Synonyms: G0S8 antibody, GOS8 antibody, fa96c08 antibody, wu:fa96c08 antibody, wu:fj08f11 antibody, zgc:91965 antibody, g0s8 antibody, regulator of G protein signaling 2 antibody, regulator of G-protein signaling 2 antibody, regulator of G-protein signaling 2, 24kDa antibody, regulator of G-protein signaling 2 L homeolog antibody, RGS2 antibody, Rgs2 antibody, rgs2 antibody, rgs2.L antibody

Background:

Background: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.

Aliases: Basic helix-loop-helix phosphoprotein G0S8 antibody, Cell growth inhibiting protein 31 antibody, Cell growth-inhibiting gene 31 protein antibody, G0 to G1 switch regulatory 8 24kD antibody, G0/G1 switch regulatory protein 8 antibody, G0S8 antibody, GOS8 antibody, OTTHUMP00000060765 antibody, Regulator of G protein signaling 2 antibody, Regulator of G protein signalling 2 24kD antibody, Regulator of G-protein signaling 2 antibody, Regulators of G protein signaling XRGSVI antibody, RGS 2 antibody, RGS2 antibody, RGS2_HUMAN antibody

UniProt: P41220

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation