RGS1 antibody (AA 14-209)

Catalog No. ABIN7167586

Product Details anti-RGS1 Antibody

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Binding Specificity: AA 14-209

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Regulator of G-protein signaling 1 protein (14-209AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Alternative Name: RGS1 (RGS1 Products)

Synonyms: 1R20 antibody, BL34 antibody, IER1 antibody, IR20 antibody, RGS1 antibody, 1r20 antibody, bl34 antibody, ier1 antibody, ir20 antibody, regulator of G protein signaling 1 antibody, regulator of G-protein signaling 1 antibody, regulator of G-protein signaling 1 S homeolog antibody, Regulator of G-protein signaling 1 antibody, RGS1 antibody, Rgs1 antibody, rgs1.S antibody, rgs1 antibody

Background:

Background: Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894). Inhibits B cell chemotaxis toward CXCL12 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541).

Aliases: 1R20 antibody, B cell activation protein BL34 antibody, B-cell activation protein BL34 antibody, BL34 antibody, Early response protein 1R20 antibody, IER 1 antibody, IER1 antibody, Immediate early response 1 B cell specific antibody, immediate-early response 1, B-cell specific antibody, IR20 antibody, Regulator of G protein signalling 1 antibody, Regulator of G-protein signaling 1 antibody, RGS 1 antibody, RGS1 antibody, RGS1_HUMAN antibody

UniProt: Q08116

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events