rala antibody (AA 1-203)

Catalog No. ABIN7167390

Product Details anti-rala Antibody

Target: rala (Ras-related Protein Ral-A (rala))

Binding Specificity: AA 1-203

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This rala antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Ral-A protein (1-203AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for rala

Target: rala (Ras-related Protein Ral-A (rala))

Alternative Name: RALA (rala Products)

Synonyms: 3010001O15Rik antibody, AW322615 antibody, Ral antibody, Rasl1 antibody, RAL antibody, v-ral simian leukemia viral oncogene A (ras related) antibody, RAS like proto-oncogene A antibody, Rala antibody, RALA antibody

Background:

Background: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Aliases: MGC48949 antibody, Ral a antibody, Ral A protein antibody, RAL antibody, RALA antibody, RALA_HUMAN antibody, Ras family small GTP binding protein RALA antibody, RAS like protein A antibody, Ras related protein RalA antibody, Ras-related protein Ral-A antibody, v ral simian leukemia viral oncogene homolog A (ras related) antibody, v ral simian leukemia viral oncogene homolog A antibody

UniProt: P11233

Pathways: Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome