RAB31 antibody (AA 1-194)

Catalog No. ABIN7167292

Product Details anti-RAB31 Antibody

Target: RAB31 (RAB31, Member RAS Oncogene Family (RAB31))

Binding Specificity: AA 1-194

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB31 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Ras-related protein Rab-31 protein (1-194AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RAB31

Target: RAB31 (RAB31, Member RAS Oncogene Family (RAB31))

Alternative Name: RAB31 (RAB31 Products)

Synonyms: RAB31 antibody, rab22b antibody, Rab22B antibody, 1700093E07Rik antibody, AI415285 antibody, Rab0 antibody, RAB31, member RAS oncogene family antibody, RAB31, member RAS oncogene family L homeolog antibody, RAB31 antibody, rab31.L antibody, rab31 antibody, Rab31 antibody

Background:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Aliases: Rab 22B antibody, RAB 31 antibody, Rab22B antibody, Rab31 antibody, RAB31 member RAS oncogene family antibody, RAB31_HUMAN antibody, Ras related protein Rab 31 antibody, Ras related protein Rab31 antibody, Ras-related protein Rab-22B antibody, Ras-related protein Rab-31 antibody

UniProt: Q13636