RIN1 antibody (AA 192-341) (HRP)

Catalog No. ABIN7167117

Product Details anti-RIN1 Antibody (HRP)

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Binding Specificity: AA 192-341

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIN1 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Ras and Rab interactor 1 protein (192-341AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RIN1

Target: RIN1 (Ras and Rab Interactor 1 (RIN1))

Alternative Name: RIN1 (RIN1 Products)

Synonyms: RIN1 antibody, Ras and Rab interactor 1 antibody, RIN1 antibody, Rin1 antibody

Background:

Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.

Aliases: RIN1 antibody, Ras and Rab interactor 1 antibody, Ras inhibitor JC99 antibody, Ras interaction/interference protein 1 antibody

UniProt: Q13671