IER3 antibody (AA 1-82) (Biotin)

Catalog No. ABIN7167055

Product Details anti-IER3 Antibody (Biotin)

Target: IER3 (Immediate Early Response 3 (IER3))

Binding Specificity: AA 1-82

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IER3 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Radiation-inducible immediate-early gene IEX-1 protein (1-82AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IER3

Target: IER3 (Immediate Early Response 3 (IER3))

Alternative Name: IER3 (IER3 Products)

Synonyms: DIF-2 antibody, DIF2 antibody, GLY96 antibody, IEX-1 antibody, IEX-1L antibody, IEX1 antibody, PRG1 antibody, AI663993 antibody, cI-3 antibody, gly96 antibody, IER3 antibody, Dif2 antibody, Iex1 antibody, Ler3 antibody, Prg1 antibody, immediate early response 3 antibody, IER3 antibody, Ier3 antibody

Background:

Background: May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Acts also as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment.

Aliases: DIF2 antibody, Differentiation-dependent gene 2 protein antibody, GLY96 antibody, IER3 antibody, IEX1_HUMAN antibody, IEX1L antibody, Immediate early protein GLY96 antibody, Immediate early response 3 antibody, Immediate early response 3 protein antibody, Immediately early gene X 1 antibody, PACAP-responsive gene 1 protein antibody, PRG 1 antibody, PRG1 antibody, Protein DIF 2 antibody, Protein DIF-2 antibody, Protein PRG1 antibody, Radiation-inducible immediate-early gene IEX-1 antibody

UniProt: P46695

Pathways: Regulation of Carbohydrate Metabolic Process