RACGAP1 antibody (AA 353-632)

Catalog No. ABIN7167019

Product Details anti-RACGAP1 Antibody

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Binding Specificity: AA 353-632

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RACGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Rac GTPase-activating protein 1 protein (353-632AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Alternative Name: RACGAP1 (RACGAP1 Products)

Synonyms: CYK4 antibody, HsCYK-4 antibody, ID-GAP antibody, MgcRacGAP antibody, cyk-4 antibody, id-gap antibody, mgcracgap antibody, RACGAP1 antibody, MGC121578 antibody, Gap antibody, RasGAP antibody, Rasa antibody, GAPX antibody, AI227039 antibody, AI327394 antibody, Band25 antibody, GTPase antibody, gtl11 antibody, mKIAA1478 antibody, wu:fb92c08 antibody, zgc:77839 antibody, Rac GTPase activating protein 1 antibody, rac GTPase-activating protein 1 antibody, Rac GTPase activating protein 1 L homeolog antibody, RAS p21 protein activator 1 antibody, Rac GTPase-activating protein 1 antibody, si:ch1073-416j23.1 antibody, RACGAP1 antibody, racgap1 antibody, racgap1.L antibody, racgap1.2.L antibody, racgap1.2 antibody, Rasa1 antibody, Racgap1 antibody, si:ch1073-416j23.1 antibody

Background:

Background: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Aliases: CYK4 antibody, GAP antibody, Gap1 antibody, GTPase activating protein antibody, HsCYK-4 antibody, ID GAP antibody, KIAA1478 antibody, Male germ cell RacGap antibody, MgcRacGAP antibody, Protein CYK4 homolg antibody, Protein CYK4 homolog antibody, Rac GTPase activating protein 1 antibody, Rac GTPase-activating protein 1 antibody, RACGAP 1 antibody, Racgap1 antibody, RGAP1_HUMAN antibody

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor