CHM antibody (AA 1-653) (HRP)
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- Target See all CHM Antibodies
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
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Binding Specificity
- AA 1-653
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHM antibody is conjugated to HRP
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Application
- ELISA
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Rab proteins geranylgeranyltransferase component A 1 protein (1-653AA)
- Isotype
- IgG
- Top Product
- Discover our top product CHM Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CHM (Choroideremia (Rab Escort Protein 1) (CHM))
- Alternative Name
- CHM (CHM Products)
- Synonyms
- CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody
- Background
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Background: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins, this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
Aliases: dy, Chm antibody, Choroideraemia protein antibody, Choroideremia antibody, DXS540 antibody, FLJ38564 antibody, GGTA antibody, HSD 32 antibody, MGC102710 antibody, Rab escort protein 1 antibody, Rab geranylgeranyltransferase component A antibody, Rab proteins geranylgeranyltransferase component A 1 antibody, RAE1_HUMAN antibody, REP 1 antibody, REP-1 antibody, REP1 antibody, TCD antibody, TCD protein antibody
- UniProt
- P24386
- Pathways
- Sensory Perception of Sound
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