TDRD12 antibody (AA 991-1164)

Catalog No. ABIN7166667

Product Details anti-TDRD12 Antibody

Target: TDRD12 (Tudor Domain Containing 12 (TDRD12))

Binding Specificity: AA 991-1164

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDRD12 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Putative ATP-dependent RNA helicase TDRD12 protein (991-1164AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TDRD12

Target: TDRD12 (Tudor Domain Containing 12 (TDRD12))

Alternative Name: TDRD12 (TDRD12 Products)

Synonyms: ECAT8 antibody, 2410004F06Rik antibody, 2410070K17Rik antibody, EG434165 antibody, tudor domain containing 12 antibody, TDRD12 antibody, Tdrd12 antibody

Background:

Background: Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.

Aliases: ECAT8 antibody, ES cell associated transcript 8 antibody, ES cell-associated transcript 8 protein antibody, TDR12_HUMAN antibody, Tdrd12 antibody, Tudor domain containing 12 antibody, Tudor domain-containing protein 12 antibody

UniProt: Q587J7