ROS1 antibody (AA 79-248) (FITC)
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- Target See all ROS1 Antibodies
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
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Binding Specificity
- AA 79-248
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ROS1 antibody is conjugated to FITC
- Application
- Please inquire
- Cross-Reactivity
- Human
- Purification
- >95%, Protein G purified
- Immunogen
- Recombinant Human Proto-oncogene tyrosine-protein kinase ROS protein (79-248AA)
- Isotype
- IgG
- Top Product
- Discover our top product ROS1 Primary Antibody
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- ROS1 (C-Ros Oncogene 1 , Receptor tyrosine Kinase (ROS1))
- Alternative Name
- ROS1 (ROS1 Products)
- Synonyms
- MCF3 antibody, ROS antibody, c-ros-1 antibody, ROS1C antibody, Ros-1 antibody, c-ros antibody, ROS proto-oncogene 1, receptor tyrosine kinase antibody, ROS proto-oncogene 1 , receptor tyrosine kinase antibody, Ros1 proto-oncogene antibody, ROS1 antibody, Ros1 antibody
- Background
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Background: Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation of VAV3, a guanine nucleotide exchange factor regulating cell morphology. May activate other downstream signaling proteins including AKT1, MAPK1, MAPK3, IRS1 and PLCG2.
Aliases: c ros 1 antibody, c ros antibody, c ros oncogene 1 receptor tyrosine kinase antibody, c Ros receptor tyrosine kinase antibody, c ros1 antibody, MCF 3 antibody, MCF3 antibody, Oncogene ROS antibody, OTTHUMP00000017814 antibody, OTTHUMP00000017815 antibody, OTTHUMP00000040389 antibody, Proto oncogene c ros 1 protein antibody, Proto oncogene c Ros antibody, Proto oncogene tyrosine protein kinase ROS antibody, Proto oncogene tyrosine protein kinase ROS precursor antibody, Proto-oncogene c-Ros-1 antibody, Proto-oncogene tyrosine-protein kinase ROS antibody, Receptor tyrosine kinase c ros oncogene 1 antibody, Ros 1 antibody, ROS 1C antibody, ROS antibody, ROS proto oncogene 1 , receptor tyrosine kinase antibody, ROS_HUMAN antibody, ROS1 antibody, ROS1C antibody, Transmembrane tyrosine specific protein kinase antibody, v ros avian UR2 sarcoma virus oncogene homolog 1 antibody, v ros UR2 sarcoma virus oncogene homolog 1 antibody
- UniProt
- P08922
- Pathways
- RTK Signaling
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