RP2 antibody (AA 1-350)

Catalog No. ABIN7166333

Product Details anti-RP2 Antibody

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Binding Specificity: AA 1-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RP2 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein XRP2 protein (1-350AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Alternative Name: RP2 (RP2 Products)

Background:

Background: Acts as a GTPase-activating protein (GAP) involved in trafficking between the Golgi and the ciliary membrane. Involved in localization of proteins, such as NPHP3, to the cilium membrane by inducing hydrolysis of GTP ARL3, leading to the release of UNC119 (or UNC119B). Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor towards ADP-ribosylation factor-like proteins.

Aliases: RP2 antibody, Protein XRP2 antibody

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process