BBS9 antibody (AA 8-185)

Catalog No. ABIN7165997

Product Details anti-BBS9 Antibody

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Binding Specificity: AA 8-185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BBS9 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein PTHB1 protein (8-185AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BBS9

Target: BBS9 (Bardet-Biedl Syndrome 9 (BBS9))

Alternative Name: BBS9 (BBS9 Products)

Synonyms: b1 antibody, B1 antibody, C18 antibody, D1 antibody, PTHB1 antibody, RGD1308472 antibody, E130103I17Rik antibody, Bardet-Biedl syndrome 9 antibody, bardet-biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 (human) antibody, BBS9 antibody, bbs9 antibody, Bbs9 antibody

Background:

Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

Aliases: B1 antibody, Bardet Biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 protein antibody, bbs9 antibody, C18 antibody, D1 antibody, MGC118917 antibody, OTTHUMP00000158833 antibody, OTTHUMP00000202918 antibody, OTTHUMP00000202919 antibody, OTTHUMP00000202920 antibody, Parathyroid hormone-responsive B1 gene protein antibody, Protein PTHB1 antibody, PTH-responsive osteosarcoma B1 protein antibody, PTHB1 antibody, PTHB1_HUMAN antibody

UniProt: Q3SYG4

Pathways: Hedgehog Signaling