PPP1R16B antibody (AA 101-400)

Catalog No. ABIN7165919

Product Details anti-PPP1R16B Antibody

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Binding Specificity: AA 101-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R16B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP1R16B

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Alternative Name: PPP1R16B (PPP1R16B Products)

Synonyms: ANKRD4 antibody, C130078N17Rik antibody, TIMAP antibody, Wdt4 antibody, protein phosphatase 1, regulatory (inhibitor) subunit 16B antibody, protein phosphatase 1 regulatory subunit 16B antibody, Ppp1r16b antibody, PPP1R16B antibody

Background:

Background: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Aliases: ANKRD4 antibody, Ankyrin repeat domain containing protein 4 antibody, ankyrin repeat domain protein 4 antibody, Ankyrin repeat domain-containing protein 4 antibody, CAAX box protein TIMAP antibody, hTIMAP antibody, KIAA0823 antibody, PP16B_HUMAN antibody, PPP1R16B antibody, Protein phosphatase 1 regulatory inhibitor subunit 16B antibody, protein phosphatase 1, regulatory (inhibitor) subunit 16B antibody, TGF beta inhibited membrane associated protein antibody, TGF-beta-inhibited membrane-associated protein antibody, TIMAP antibody

UniProt: Q96T49