SGK196 antibody (AA 44-350) (Biotin)

Catalog No. ABIN7165888

Product Details anti-SGK196 Antibody (Biotin)

Target: SGK196 (Protein Kinase Protein SgK196 (SGK196))

Binding Specificity: AA 44-350

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGK196 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein O-mannose kinase protein (44-350AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SGK196

Target: SGK196 (Protein Kinase Protein SgK196 (SGK196))

Alternative Name: POMK (SGK196 Products)

Synonyms: MDDGA12 antibody, SGK196 antibody, Sgk196 antibody, RGD1310810 antibody, sgk196 antibody, wu:fc58e12 antibody, protein-O-mannose kinase antibody, protein-O-mannose kinase L homeolog antibody, POMK antibody, Pomk antibody, pomk antibody, pomk.L antibody

Background:

Background: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

Aliases: FLJ23356 antibody, MDDGA12 antibody, POMK antibody, Probable inactive protein kinase-like protein SgK196 antibody, Protein kinase like protein SgK196 antibody, Protein kinase-like protein SgK196 antibody, Protein O-mannose kinase antibody, SG196_HUMAN antibody, SGK196 antibody, Sugen kinase 196 antibody

UniProt: Q9H5K3