WDYHV1 antibody (N-Term)

Catalog No. ABIN7165841

Product Details anti-WDYHV1 Antibody

Target: WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

Binding Specificity: AA 1-205, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDYHV1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein N-terminal glutamine amidohydrolase protein (1-205AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for WDYHV1

Target: WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

Alternative Name: WDYHV1 (WDYHV1 Products)

Synonyms: ntaq1 antibody, C8orf32 antibody, 2410187C16Rik antibody, AU014961 antibody, AW550036 antibody, Ntaq1 antibody, RGD1311362 antibody, C14H8orf32 antibody, si:rp71-45k5.3 antibody, WDYHV motif containing 1 antibody, WDYHV motif containing 1 S homeolog antibody, WDYHV1 antibody, wdyhv1.S antibody, wdyhv1 antibody, Wdyhv1 antibody

Background:

Background: Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine (By similarity).

Aliases: WDYHV1 antibody, C8orf32 antibody, NTAQ1 antibody, Protein N-terminal glutamine amidohydrolase antibody, EC 3.5.1.122 antibody, Protein NH2-terminal glutamine deamidase antibody, N-terminal Gln amidase antibody, Nt(Q)-amidase antibody, WDYHV motif-containing protein 1 antibody

UniProt: Q96HA8