MAEL antibody (AA 1-200)

Catalog No. ABIN7165779

Product Details anti-MAEL Antibody

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Binding Specificity: AA 1-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAEL antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein maelstrom homolog protein (1-200AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MAEL

Target: MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))

Alternative Name: MAEL (MAEL Products)

Synonyms: CT128 antibody, RP11-102C16.1 antibody, SPATA35 antibody, 4933405K18Rik antibody, AU019877 antibody, RGD1309333 antibody, maelstrom spermatogenic transposon silencer antibody, MAEL antibody, Mael antibody

Background:

Background: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity).

Aliases: cancer/testis antigen 128 antibody, CT128 antibody, FLJ14904 antibody, mael antibody, MAEL_HUMAN antibody, maelstrom homolog (Drosophila) antibody, Maelstrom homolog antibody, OTTHUMP00000032344 antibody, Protein maelstrom homolog antibody, RP11-102C16.1 antibody

UniProt: Q96JY0