MTDH antibody (AA 1-260)

Catalog No. ABIN7165774

Product Details anti-MTDH Antibody

Target: MTDH (Metadherin (MTDH))

Binding Specificity: AA 1-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTDH antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein LYRIC protein (1-260AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MTDH

Target: MTDH (Metadherin (MTDH))

Alternative Name: MTDH (MTDH Products)

Synonyms: MGC75963 antibody, 2610103J23Rik antibody, 3D3 antibody, 3D3/Lyric antibody, AEG-1 antibody, AV353288 antibody, D8Bwg1112e antibody, Lyric antibody, AEG1 antibody, LYRIC antibody, LYRIC/3D3 antibody, metadherin antibody, mtdh antibody, MTDH antibody, Mtdh antibody

Background:

Background: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Aliases: 3D3 antibody, 3D3/LYRIC antibody, AEG 1 antibody, AEG-1 antibody, AEG1 antibody, Astrocyte elevated gene 1 antibody, Astrocyte elevated gene-1 protein antibody, LYRIC antibody, LYRIC/3D3 antibody, LYRIC_HUMAN antibody, Lysine rich CEACAM1 associated protein antibody, Lysine rich CEACAM1 co isolated protein antibody, Lysine-rich CEACAM1 co-isolated protein antibody, Metadherin antibody, Metastasis adhesion protein antibody, MTDH antibody, Protein LYRIC antibody

UniProt: Q86UE4

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization