LIN7A antibody (AA 1-233) (HRP)

Catalog No. ABIN7165761

Product Details anti-LIN7A Antibody (HRP)

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Binding Specificity: AA 1-233

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIN7A antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein lin-7 homolog A protein (1-233AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for LIN7A

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Alternative Name: LIN7A (LIN7A Products)

Synonyms: LIN-7A antibody, LIN7 antibody, MALS-1 antibody, TIP-33 antibody, VELI1 antibody, lin7b antibody, zgc:73090 antibody, AI848705 antibody, Veli antibody, Veli1 antibody, lin-7 homolog A, crumbs cell polarity complex component antibody, lin-7 homolog A (C. elegans) antibody, LIN7A antibody, lin7a antibody, Lin7a antibody

Background:

Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Aliases: hLin-7 antibody, Lin 7 homolog A (C. elegans) antibody, LIN 7A antibody, Lin-7A antibody, LIN7 antibody, LIN7A antibody, LIN7A_HUMAN antibody, MALS-1 antibody, Mammalian LIN 7 1 antibody, Mammalian lin-seven protein 1 antibody, Protein lin-7 homolog A antibody, Tax interaction protein 33 antibody, TIP-33 antibody, Veli-1 antibody, VELI1 antibody, Vertebrate lin-7 homolog 1 antibody, Vertebrate LIN7 homolog 1 antibody

UniProt: O14910

Pathways: Synaptic Membrane