IMPACT antibody (AA 41-320)

Catalog No. ABIN7165645

Product Details anti-IMPACT Antibody

Target: IMPACT (Impact Homolog (IMPACT))

Binding Specificity: AA 41-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IMPACT antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein IMPACT protein (41-320AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IMPACT

Target: IMPACT (Impact Homolog (IMPACT))

Alternative Name: IMPACT (IMPACT Products)

Synonyms: zgc:103672 antibody, Ximpact antibody, impact-A antibody, RWDD5 antibody, impact-a antibody, E430016J11Rik antibody, impact RWD domain protein antibody, impact antibody, impact RWD domain protein L homeolog antibody, impact, RWD domain protein antibody, IMPACT antibody, impact antibody, EDI_298310 antibody, impact.L antibody, Impact antibody

Background:

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis.

Aliases: IMPACT antibody, Impact homolog (mouse) antibody, Impact homolog antibody, impact RWD domain protein antibody, IMPCT_HUMAN antibody, Imprinted and ancient gene protein homolog antibody, MGC33718 antibody, Protein IMPACT antibody, RWD domain containing 5 antibody, RWDD5 antibody

UniProt: Q9P2X3