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IMPACT antibody (AA 41-320)

IMPACT Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7165645
  • Target See all IMPACT Antibodies
    IMPACT (Impact Homolog (IMPACT))
    Binding Specificity
    • 15
    • 14
    • 7
    • 5
    • 2
    • 1
    AA 41-320
    Reactivity
    • 22
    • 16
    • 16
    Human
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 9
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IMPACT antibody is un-conjugated
    Application
    • 33
    • 19
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Protein IMPACT protein (41-320AA)
    Isotype
    IgG
  • Application Notes
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    IMPACT (Impact Homolog (IMPACT))
    Alternative Name
    IMPACT (IMPACT Products)
    Synonyms
    zgc:103672 antibody, Ximpact antibody, impact-A antibody, RWDD5 antibody, impact-a antibody, E430016J11Rik antibody, impact RWD domain protein antibody, impact antibody, impact RWD domain protein L homeolog antibody, impact, RWD domain protein antibody, IMPACT antibody, impact antibody, EDI_298310 antibody, impact.L antibody, Impact antibody
    Background

    Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis.

    Aliases: IMPACT antibody, Impact homolog (mouse) antibody, Impact homolog antibody, impact RWD domain protein antibody, IMPCT_HUMAN antibody, Imprinted and ancient gene protein homolog antibody, MGC33718 antibody, Protein IMPACT antibody, RWD domain containing 5 antibody, RWDD5 antibody

    UniProt
    Q9P2X3
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