DDI2 antibody (AA 1-211)

Catalog No. ABIN7165250

Product Details anti-DDI2 Antibody

Target: DDI2 (DNA-Damage Inducible 1 Homolog 2 (DDI2))

Binding Specificity: AA 1-211

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDI2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein DDI1 homolog 2 protein (1-211AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for DDI2

Target: DDI2 (DNA-Damage Inducible 1 Homolog 2 (DDI2))

Alternative Name: DDI2 (DDI2 Products)

Synonyms: RP4-680D5.5 antibody, 1110056G13Rik antibody, 1700027M01Rik antibody, 9130022E05Rik antibody, AI604911 antibody, AU040698 antibody, zgc:63515 antibody, DNA damage inducible 1 homolog 2 antibody, DNA-damage inducible protein 2 antibody, DNA damage inducible 1 homolog 2 L homeolog antibody, DDI2 antibody, Ddi2 antibody, ddi2 antibody, ddi2.L antibody

Background:

Background: Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at \\\'Leu-104\\\', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane (PubMed:27676298, PubMed:27528193). Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1 (PubMed:27528193).

Aliases: DDI1 DNA damage inducible 1 homolog 2 antibody, Ddi2 antibody, DDI2_HUMAN antibody, DNA damage inducible 1 homolog 2 (S. cerevisiae) antibody, DNA damage inducible 1 homolog 2 antibody, DNA damage inducible protein 2 antibody, MGC14844 antibody, Protein DDI1 homolog 2 antibody, RP4-680D5.5 antibody

UniProt: Q5TDH0