CYR61 antibody (AA 25-381) (Biotin)

Catalog No. ABIN7165239

Product Details anti-CYR61 Antibody (Biotin)

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Binding Specificity: AA 25-381

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYR61 antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein CYR61 protein (25-381AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CYR61

Target: CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))

Alternative Name: CYR61 (CYR61 Products)

Synonyms: CCN1 antibody, GIG1 antibody, IGFBP10 antibody, ccn1 antibody, gig1 antibody, Xcyr61 antibody, igfbp10 antibody, MGC69281 antibody, MGC69539 antibody, cyr61-l2 antibody, zgc:158158 antibody, CYR61 antibody, AI325051 antibody, Igfbp10 antibody, cysteine rich angiogenic inducer 61 antibody, cysteine-rich, angiogenic inducer, 61 antibody, cysteine-rich, angiogenic inducer, 61 like 2 antibody, cysteine rich protein 61 antibody, cysteine rich angiogenic inducer 61 S homeolog antibody, CYR61 antibody, Cyr61 antibody, cyr61 antibody, cyr61l2 antibody, cyr61.S antibody

Background:

Background: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3.

Aliases: 3CH61 antibody, CCN 1 antibody, CCN family member 1 antibody, CCN1 antibody, CYR 61 antibody, Cyr61 antibody, CYR61 protein antibody, CYR61_HUMAN antibody, Cysteine rich angiogenic inducer 61 antibody, Cysteine rich heparin binding protein 61 antibody, Cysteine-rich angiogenic inducer 61 antibody, GIG 1 antibody, GIG1 antibody, IBP-10 antibody, IGF-binding protein 10 antibody, Igfbp 10 antibody, IGFBP-10 antibody, Igfbp10 antibody, Insulin like growth factor binding protein 10 antibody, Insulin-like growth factor-binding protein 10 antibody, Protein CYR61 antibody, Protein GIG1 antibody

UniProt: O00622

Pathways: Positive Regulation of Endopeptidase Activity, Growth Factor Binding