CBY1/PGEA1 antibody (AA 1-126)

Catalog No. ABIN7165200

Product Details anti-CBY1/PGEA1 Antibody

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Binding Specificity: AA 1-126

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBY1/PGEA1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Purification: Antigen Affinity Purified

Immunogen: Recombinant Human Protein chibby homolog 1 protein (1-126AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CBY1/PGEA1

Target: CBY1/PGEA1 (CBY1) (Chibby Homolog 1 (CBY1))

Alternative Name: CBY1 (CBY1 Products)

Synonyms: chibby antibody, cby antibody, arb1 antibody, pgea1 antibody, pigea14 antibody, pigea-14 antibody, hs508i15a antibody, C22orf2 antibody, CBY antibody, HS508I15A antibody, PGEA1 antibody, PIGEA-14 antibody, PIGEA14 antibody, 1110014P06Rik antibody, PGEA14 antibody, Pgea1 antibody, chibby homolog 1 S homeolog antibody, chibby homolog 1 antibody, chibby family member 1, beta catenin antagonist antibody, cby1.S antibody, cby1 antibody, CBY1 antibody, Cby1 antibody

Background:

Background: Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

Aliases: ARPP-binding protein antibody, C22orf2 antibody, CBY antibody, Cby1 antibody, CBY1_HUMAN antibody, Cytosolic leucine rich protein antibody, Cytosolic leucine-rich protein antibody, Golgi and endoplasmic reticulum-associated 1 antibody, HRIHFB2025 antibody, PIGEA 14 antibody, PIGEA-14 antibody, PKD2 interactor antibody, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 antibody, Protein Chibby antibody, Protein chibby homolog 1 antibody

UniProt: Q9Y3M2