BEX2 antibody (AA 1-128) (HRP)

Catalog No. ABIN7165130

Product Details anti-BEX2 Antibody (HRP)

Target: BEX2 (Brain Expressed X-Linked 2 (BEX2))

Binding Specificity: AA 1-128

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BEX2 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein BEX2 protein (1-128AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for BEX2

Target: BEX2 (Brain Expressed X-Linked 2 (BEX2))

Alternative Name: BEX2 (BEX2 Products)

Synonyms: BEX1 antibody, DJ79P11.1 antibody, AL024066 antibody, Bex1 antibody, EG2RVC antibody, brain expressed X-linked 2 antibody, BEX2 antibody, Bex2 antibody

Background:

Background: Regulator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated through the modulation of BCL2 protein family, which involves the positive regulation of anti-apoptotic member BCL2 and the negative regulation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells through the regulation of CCND1 and CDKN1A. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity.

Aliases: BEX2Protein BEX2 antibody, Brain-expressed X-linked protein 2 antibody, hBex2 antibody

UniProt: Q9BXY8