AGO4 antibody (AA 716-861)

Catalog No. ABIN7165099

Product Details anti-AGO4 Antibody

Target: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Binding Specificity: AA 716-861

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGO4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Protein argonaute-4 protein (716-861aa)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IF:1:100-1:500,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for AGO4

Target: AGO4 (EIF2C4) (Eukaryotic Translation Initiation Factor 2C, 4 (EIF2C4))

Alternative Name: AGO4 (EIF2C4 Products)

Synonyms: EIF2C4 antibody, ago4 antibody, Argonaute4 antibody, argonaute-4 antibody, eif2c4 antibody, wu:fd14f04 antibody, ARGONAUTE 4 antibody, OCP11 antibody, OVEREXPRESSOR OF CATIONIC PEROXIDASE 11 antibody, T20P8.9 antibody, T20P8_9 antibody, Eif2c4 antibody, 5730550L01Rik antibody, AI481660 antibody, argonaute 4, RISC catalytic component antibody, argonaute 1, RISC catalytic component antibody, argonaute RISC catalytic component 4 antibody, Argonaute family protein antibody, argonaute 4, RISC catalytic component L homeolog antibody, argonaute RISC catalytic subunit 4 antibody, AGO4 antibody, ago1 antibody, ago4 antibody, Ago4 antibody, ago4.L antibody

Background:

Background: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV).

Aliases: Protein argonaute-4 (Argonaute4) (hAgo4) (Argonaute RISC catalytic component 4) (Eukaryotic translation initiation factor 2C 4) (eIF-2C 4) (eIF2C 4), AGO4, EIF2C4 KIAA1567

UniProt: Q9HCK5

Pathways: Fc-epsilon Receptor Signaling Pathway, Regulatory RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Cellular Glucan Metabolic Process