Prolactin Receptor antibody (AA 330-548)

Catalog No. ABIN7164726

Product Details anti-Prolactin Receptor Antibody

Target: Prolactin Receptor (PRLR)

Binding Specificity: AA 330-548

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Prolactin receptor protein (330-548AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR (PRLR Products)

Synonyms: hPRLrI antibody, PRL-R antibody, prlr antibody, PRLRb antibody, PRLR antibody, tprlr antibody, DKFZp469D061 antibody, RATPRLR antibody, AI987712 antibody, Pr-1 antibody, Pr-3 antibody, Prlr-rs1 antibody, wu:fj65c07 antibody, prolactin receptor antibody, prolactin receptor L homeolog antibody, prolactin receptor S homeolog antibody, prolactin receptor a antibody, PRLR antibody, prlr.L antibody, prlr.S antibody, PR antibody, prlr antibody, Prlr antibody, prlra antibody

Background:

Background: This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.

Aliases: AI987712 antibody, CLONE SPM213 antibody, CPRLP antibody, Delta 4-delta 7/11 truncated prolactin receptor antibody, Delta 4-SF1b truncated prolactin receptor antibody, HPRL antibody, hPRL receptor antibody, hPRLrI antibody, Lactogen receptor antibody, MFAB antibody, MGC105486 antibody, OPR antibody, OTTHUMP00000115998 antibody, Pr-1 antibody, Pr-3 antibody, PRL R antibody, PRL-R antibody, PRLR antibody, Prlr-rs1 antibody, PRLR_HUMAN antibody, Prolactin receptor a antibody, Prolactin receptor antibody, Prolactin receptor delta 7/11 antibody, RATPRLR antibody, Secreted prolactin binding protein antibody, Truncated testis-specific box 1-C prolactin receptor antibody, wu:fj65c07 antibody

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus